Cerebrovascular accident

Approximately 120,000 people in the Netherlands live with the consequences of a stroke. Each year 30.000 patients suffer a stroke as a result of a cerebral infarct or haemorrhage. Cerebral vascular accidents are the third largest cause of death in the Netherlands and are the most important cause of invalidity in the elderly. In 80% of the cases the cause is a cerebral infarct, whereby a part of the brain receives no oxygen and dies as a result of a blocked blood vessel. In 20% of the cases it involves a cerebral haemorrhage. Treatment of a cerebral infarct and a cerebral haemorrhage differ. Approximately 25% will suffer a new stroke within 5 years. 


Improvement in the dissemination of information, prevention of, and research on CVA's is being addressed in various ways. This takes place in conjunction with charities (Hartstichting  and Hersenstichting ) and the Dutch CVA patient society "Samen Verder". It is highly desirable that in the long term a European Consortium be formed to coordinate large therapeutic research with the help of clinical data and biobanks. The European Stroke Organisation is a European collaboration, but as far is known there are no developments in the area of European biobanks. 

Overview

Contact person

a.algra@umcutrecht.nl

Main features

Donors

5308

Age cohort

11-98

Phenotypes

Subarachnoid haemorrhage Intracerebral haemorrhage Cerebral infarction Nonpyogenic thrombosis of intracranial venous system

Types of data

Medical records Biological samples

Materials collected

DNA Plasma Serum Urine Feaces Tissue, cryo preserved Tissue, paraffin preserved RNA peripheral blood cells Other

Data enrichment

Genomics