Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic infection of the digestive canal, wherefore no clear cause can be determined. 

Afbeelding IBDThe two most important forms of IBD are Crohn’s disease and Ulcerative colitis. IBD patients have chronic abdominal pain, (bloody) diarrhoea, weight loss and sometimes anaemia. The majority of patients undergo surgery and need long term medication in the form of non-specific anti-inflammatories. 

Improvement in the dissemination of information, prevention, and research is being addressed in various ways. This takes place in conjunction with the Maag Lever Darm Stichting, the patient society CCUVN (Crohn en Colitis Vereniging Nederland) and ECCO (European Crohn's & Colitis Organization).

The ICC (Initiative on Crohn's and Colitis) is a collaboration between the eight UMC's in the area of IBD. The ICC’s mission is to improve the quality of life for IBD patients through scientific research into the pathogenesis of IBD and through the development and application of new therapy (treatment innovation). Read more

The Parelsnoer Institute’s biobank model has been successfully exported to other EU countries in the context of the European ECCO Biobank initiative.

Overview

Contact person

IBDParel@umcg.nl

Main features

Donors

4098

Age cohort

17-90

Phenotypes

Crohn disease [regional enteritis] Ulcerative colitis

Types of data

Medical records Biological samples

Materials collected

DNA Plasma Serum Urine Feaces Tissue, cryo preserved Tissue, paraffin preserved RNA peripheral blood cells Other

Data enrichment

Genomics